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A wide variety of assay products for identifying and analyzing of proteins and their functions. Products utilize various detection methods and sample types and can be used for applications including medical, cellular, molecular, and protein research.
Allows propagation and banking of the ADCC Bioassay, F Variant, Effector Cells without the complex workflow and variability inherent in primary cell-based assays. The bioassay also can be used to quantify effects of antibody glycosylation on Fc effector function.
PPARG Transcription Factor Assay Kit is a non-radioactive, sensitive method for detecting PPARG transcription factor DNA binding activity in nuclear extracts.
AKT/PKB Signaling Phospho-Specific Array includes 216 highly specific and well-characterized phosphorylation antibodies in the AKT/PKB signaling pathway.
The Proteasome-Glo™ Cell-Based Assays are homogeneous, luminescent assays that measure the chymotrypsin-like, trypsin-like and caspase-like protease activities associated with the proteasome complex in a purified enzyme preparation.
Provides a biologically relevant and specific mechanism-of-action-based measure of ADCC without the complex workflow and variability inherent in primary cell-based assays. The bioassay also can be used to quantify effects of antibody glycosylation on Fc effector function.
Recombinant full-length human PDK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. PDK1 (3-phosphoinositide-dependent protein kinase) is activated by the presence of PtdIns(3,4,5)P3 or PtdIns(3,4)P2.
Cell Cycle Control Phospho-Specific Array includes 238 highly specific and well-characterized phosphorylation antibodies in the regulation of cell cycle.
DNA-Dependent Protein Kinase Peptide Substrate is a highly specific substrate for DNA-PK, with the sequence Glu-Pro-Pro-Leu-Ser-Gln-Glu-Ala-Phe-Ala-Asp-Leu-Trp-Lys-Lys.
Generate C-Terminal Fusions to NanoLuc™ Luciferase Reporter. The pFC32A and pFC32K Nluc CMV-neo Flexi™ Vectors use a directional cloning method based on two rare-cutting restriction enzymes, SgfI and PmeI, and contain a mammalian selectable marker to create a stable line.
NanoLuc (Nluc) luciferase is a small bright luminescent reporter enzyme (19.1kDa) engineered for optimal performance. Use the pNL3.2.CMV Vector as a negative control in experiments measuring regulated changes in NanoLuc luciferase expression.